Optimal use of SGLT2 inhibitors in diabetic kidney transplant recipients

نویسندگان

چکیده

Sodium-glucose cotransporter 2 inhibitor (SGLT2i), a glucosuric agent initially approved for use as an antidiabetic agent, was unexpectedly found to confer cardio-and reno-protective effects in individuals with or without type diabetes mellitus. Despite mounting evidence suggesting that SGLT2i provides cardio- and benefits both diabetic non-diabetic chronic kidney disease (CKD) patients the general population, reservations its transplant setting persist due concerns increased risk of genital mycotic urinary tract infections. A comprehensive review literature on efficacy safety recipients is herein presented followed by authors’ opinion optimal this patient population.

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ژورنال

عنوان ژورنال: Frontiers in nephrology

سال: 2022

ISSN: ['2813-0626']

DOI: https://doi.org/10.3389/fneph.2022.1014241